Estrogen loss a risk factor for disc degeneration, back pain

A new study has found estrogen loss in menopause is a risk factor for lumbar disc degeneration and lower back pain. Photo by Africa Studio/Shutterstock

June 14 (UPI) — A new study has found a link between the loss of estrogen in menopause and a risk for disc degeneration and lower back pain.

Research from China shows that menopause is associated with severity of disc degeneration in the lumbar spine.

The study, published June 14 in Menopause, consisted of an MRI study of 1,566 women and 1,382 men in an age-matched comparison of lumbar disc degeneration.

Previous research shows the association of estrogen deficiency in disc degeneration, but this is the first to compare age-matched men to menopausal women.

“This study shows that menopause is associated with more severe disc degeneration,” Dr. JoAnn Pinkerton, executive director of the North American Menopause Society, said in a press release. “Prevention of disc degeneration of the lumbar spine may be another potential benefit for symptomatic menopausal women who may be candidates for hormone therapy.”

The study showed younger, age-matched men were more vulnerable to disc degeneration than premenopausal women, however, postmenopausal women developed more severe disc degeneration than age-matched men compared with premenopausal and perimenopausal women.

Researchers found the most drastic difference in disc degeneration occurred in the first 15 years after the onset of menopause.

Researchers said further studies are needed to know whether age or menopause has a more vital role in the progression of disc degeneration.


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