Officials said up to 29 people were treated including 23 correction officers, four nurses and two inmates, Ohio’s WLWT reported.
Another 31 inmates in the contaminated cell block who weren’t affected by the exposure were removed and taken to a separate facility.
The victims were taken to Adena hospital and decontaminated upon entry. The hospital was placed on lockdown and some medical staff also became ill while treating the victims and were treated and decontaminated.
Officials said there were no deaths.
Dr. Kirk Tucker of Adena hospital said medical staff believes the substance in question was fentanyl, because all of the exposed patients reacted to Narcan.
“This could have been a lot worse,” Tucker said.
The cause of the exposure wasn’t immediately clear and the prison was supplied with an additional 300 doses of Narcan to treat subsequent exposures.